# Determining mutation frequency?

**URL:** <https://nextstrain.discourse.group/t/determining-mutation-frequency/292>\
**Category:** Uncategorized\
**Created:** [January 20, 2021, 6:25pm UTC](https://nextstrain.discourse.group/t/determining-mutation-frequency/292 "2021-01-20T18:25:24Z")\
**Posts on this page:** 5\
**Page:** 1

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**Author:** ![krodino](https://avatars.discourse-cdn.com/v4/letter/k/c37758/32.png) [@krodino](https://nextstrain.discourse.group/u/krodino)\
**Post date:** [January 20, 2021, 6:25pm UTC](https://nextstrain.discourse.group/t/determining-mutation-frequency/292/1 "2021-01-20T18:25:24Z")

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Is it possible to query a specific mutation and determine the frequency at which it is present? Example: How frequently is C29200A found?

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**Author:** ![rneher](https://yyz1.discourse-cdn.com/flex031/user_avatar/nextstrain.discourse.group/rneher/32/20_2.png) [@rneher](https://nextstrain.discourse.group/u/rneher)\
**Post date:** [January 23, 2021, 1:15pm UTC](https://nextstrain.discourse.group/t/determining-mutation-frequency/292/2 "2021-01-23T13:15:29Z")

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You can color by this mutation and the frequency panel will then show the frequency over time:

[https://nextstrain.org/ncov/global?c=gt-nuc\_29200](https://nextstrain.org/ncov/global?c=gt-nuc_29200)

but this will only show the frequency of the tips included in the tree, not the entire data set.

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**Author:** ![cwouters](https://avatars.discourse-cdn.com/v4/letter/c/85f322/32.png) [@cwouters](https://nextstrain.discourse.group/u/cwouters)\
**Post date:** [August 9, 2022, 1:13am UTC](https://nextstrain.discourse.group/t/determining-mutation-frequency/292/3 "2022-08-09T01:13:25Z")

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I was wondering if others know whether anything has changed since Jan '21 in terms of being able to determine the frequency of a specific mutation in GISAID database over time, or if anyone knows which other platforms may provide this information if nextstrain cannot? Using the above example, is there a way for the frequency of the C29200A mutation to be traced over time? Thanks!

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**Author:** ![aamtemp](https://avatars.discourse-cdn.com/v4/letter/a/a8b319/32.png) [@aamtemp](https://nextstrain.discourse.group/u/aamtemp)\
**Post date:** [August 9, 2022, 3:25pm UTC](https://nextstrain.discourse.group/t/determining-mutation-frequency/292/4 "2022-08-09T15:25:02Z")

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[cov-spectrum.org](http://cov-spectrum.org) has a lot of functionality related to searching for specific mutations in gisaid!

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**Author:** ![cwouters](https://avatars.discourse-cdn.com/v4/letter/c/85f322/32.png) [@cwouters](https://nextstrain.discourse.group/u/cwouters)\
**Post date:** [August 9, 2022, 3:26pm UTC](https://nextstrain.discourse.group/t/determining-mutation-frequency/292/5 "2022-08-09T15:26:58Z")

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This works great, thanks very much for the quick response!